This Challenge is requesting new design solutions for biologically based sensors for use in water systems that can detect the activation of one or more human toxicity pathways. Toxicity pathways are the perturbations to normal biological processes that occur due to exposure to a stressor, such as a chemical, that has the potential to lead to adverse health effects. Although the sensor might not identify a specific contaminant/toxin, it should be able to measure or quantitate the level of activation of one or more toxicity pathways when the sensor is exposed to water that contains relevant amounts of contaminants/toxins targeting the pathway(s). The solution should be less costly, more efficient, and more rapid than current methods for water toxicity analysis. This Theoretical Challenge is Stage 1; there is the potential for Stage 2, which would consist of a Challenge to produce a prototype.
Preview this opportunity in